Search Result

Search Results for " protein c inhibitor "

Targets

191

Compounds

Natural Products

Recombinant Proteins

Libraries

Cat No.	Product Name	Synonyms	Targets
T17148	TPPB		PKC
	TPPB is a kinase C activator of cell-permeable benzolactam-derived protein (Ki: 11.9 nM).		PKC
T2097	C-7280948	C7280948	Histone Methyltransferase
	C-7280948 is a PRMT1 inhibitor.		Histone Methyltransferase
T12494	PKC-IN-1		PKC
	PKC-IN-1 is an ATP-competitive and reversible conventional PKC enzymes inhibitor (PKCα, PKCβI, PKCβII, PKCθ, PKCγ, PKC mu and PKCε with IC50s of 2.3, 8.1, 7.6, 25.6, 57.5, 314, 808 nM, respectively).		PKC
T8764	PKC-iota inhibitor 1		PKC
	PKC-iota inhibitor 1 is an inhibitor of protein kinase C-iota (PKC-ι ; IC50 : 0.34 μM)		PKC
T13314	VTX-27		PKC
	VTX-27 is a selective inhibitor of protein kinase C θ (PKC θ) (Kis: 0.08 nM and 16 nM for PKC θ and PKC δ).		PKC
T2441	TAS-301	TAS 301	PKC
	TAS-301, an inhibitor of smooth muscle cell migration and proliferation, inhibits intimal thickening after balloon injury to rat carotid arteries.		PKC
T35407	Ζ-Stat		PKC
	ζ-Stat (NSC37044), a specific and atypical inhibitor of PKC-ζ with an IC50 of 5 μM, demonstrates the ability to inhibit proliferation and induce apoptosis in melanoma cell lines, exhibiting antitumor activity in vitro[1]...		PKC
T7648	HA-100		Myosin , PKA , PKC
	HA-100 is an inhibitor of protein kinase		Myosin , PKA , PKC
T7659	Bisindolylmaleimide IV		Others , PKC
	Bisindolylmaleimide IV is a protein kinase C (PKC) cell permeable inhibitor( IC50 : 0.10 - 0.55 μM)		Others , PKC
T7885	Afuresertib hydrochloride		ROCK , Akt , PKC
	Afuresertib hydrochloride is an inhibitor of Akt kinase (Kis of 0.08/2/2.6 nM for Akt1/Akt2/Akt3 respectively)		ROCK , Akt , PKC
TQ0028	EX229	Compound 991,C991	AMPK
	EX229 (C991) is an allosteric activator of AMPK, with Kds of 0.06 μM, 0.06 μM and 0.51 μM for α1β1γ1, α2β1γ1, and α1β2γ1, respectively.		AMPK
T1911	Afuresertib	GSK2110183C,GSK2110183	ROCK , Akt , PKC
	Afuresertib (GSK2110183) is an orally bioavailable inhibitor of the serine/threonine protein kinase Akt (protein kinase B) with potential antineoplastic activity.		ROCK , Akt , PKC
T14989	CMPD101		ROCK , GRK , PKC
	CMPD101 is a membrane-permeable small-molecule inhibitor of GRK2/3 (IC50: 18 nM and 5.4 nM). Which can be used for the study of heart failure. CMPD101 exhibits less selectively against GRK1, GRK5, ROCK-2 and PKCα with I...		ROCK , GRK , PKC
T1977	Dorsomorphin	Compound C,BML-275	AMPK , Autophagy , TGF-beta/Smad
	Dorsomorphin (BML-275) is an AMPK inhibitor (Ki=109 nM) that is selective and ATP-competitive. Dorsomorphin inhibits the BMP type I receptors ALK2, ALK3, and ALK6. Dorsomorphin induces autophagy, and possesses antitumor ...		AMPK , Autophagy , TGF-beta/Smad
T6278	Sotrastaurin	AEB071	PKC
	Sotrastaurin (AEB071) is a potent pan-PKC inhibitor (Kis: 0.95/0.64/2.1/3.2/1.8/0.22 nM for PKCα/βI/δ/ε/η/θ).		PKC
TP1563	Gap19		Gap Junction Protein
	Gap19 is a peptide that corresponds to a sequence on the cytoplasmic loop (CL) of Cx43.		Gap Junction Protein
T5600	Darovasertib	LXS196	PKC
	Darovasertib (LXS196) is a potent, selective and orally active protein kinase C (PKC) inhibitor(IC50 values of 1.9 nM, 0.4 nM and 3.1 μM for PKCα, PKCθ and GSK3β, respectively).		PKC
T6515	Go6976	Gö 6976	PKC
	Go6976 is a small molecule inhibitor of protein kinase C (PKC). Go6976 has been widely used in biomedical research as a tool to study the role of PKC in various physiological and pathophysiological processes.		PKC
T6313	Go 6983	Goe 6983	PKC
	Go 6983 is a pan-PKC inhibitor targeting PKCα, PKCβ, PKCγ, PKCδ, and PKCζ, exhibiting IC50 values of 7 nM, 7 nM, 6 nM, 10 nM, and 60 nM, respectively.		PKC
T14069	A-3 hydrochloride		CaMK , Casein Kinase , PKA , PKC
	A-3 hydrochloride is a potent, cell-permeable, reversible, ATP-competitive non-selective antagonist of various kinases. A-3 hydrochloride also inhibits PKC and casein kinase I with Ki values of 47 µM and 80 µM, respectiv...		CaMK , Casein Kinase , PKA , PKC
T6280	Enzastaurin	LY317615	Apoptosis , PKC , Autophagy
	Enzastaurin (LY317615) (LY317615) is an effective PKCβ selective inhibitor (IC50: 6 nM), 6- to 20-fold selectivity against PKCα/γ/ε.		Apoptosis , PKC , Autophagy
T7604	Valrubicin	Valstar,AD-32	Antibiotic , PKC
	Valrubicin (AD-32) (AD 32) inhibits TPA- and PDBu-induced PKC activation (IC50s: 0.85 and 1.25 μM) and has antitumor and anti-inflammatory activity.		Antibiotic , PKC
T26019	R59949	R-59949,R 59949	Others , PKC
	R59949 is used as a Diacylglycerol kinase (DGK) inhibitor.		Others , PKC
T8376	PKCβ inhibitor 1	KUN79359	Apoptosis , PKC
	PKCβ inhibitor 1 (KUN79359)(KUN79359) is a potent, selective and ATP-competitive inhibitor of PKC isozymes(IC50s of 21 and 5 nM for human PKCβ1 and PKCβ2, respectively).		Apoptosis , PKC
T14943	CGP60474		VEGFR , CDK , PKC
	CGP60474 is an inhibitor of VEGFR-2 (IC50 = 84 nM) and an inhibitor of ATP-competitive PKC. CGP60474 is also a highly potent anti-endotoxemic agent and inhibits cyclin-dependent kinase (CDK) potently.		VEGFR , CDK , PKC
T6146	Dorsomorphin dihydrochloride	BML-275 2HCl,Compound C dihydrochloride,Dorsomorphin (Compound C) 2HCl,Compound C 2HCl,BML-275 dihydrochloride	AMPK , Autophagy , TGF-beta/Smad
	Dorsomorphin dihydrochloride (BML-275 2HCl) is a potent, selective and ATP-competitive AMPK inhibitor (Ki: 109 nM) and does not exhibit significant activity on structurally related kinases.		AMPK , Autophagy , TGF-beta/Smad
T11740	Delcasertib	KAI-9803,BMS-875944	PKC
	Delcasertib (KAI-9803) is a potent and selective inhibitor of δ-protein kinase C (δPKC).		PKC
T12148	N-Desmethyltamoxifen hydrochloride		Estrogen Receptor/ERR , Endogenous Metabolite , PKC
	N-Desmethyltamoxifen hydrochloride is the major tamoxifen metabolite in humans.		Estrogen Receptor/ERR , Endogenous Metabolite , PKC
T10549	Bisindolylmaleimide VIII acetate	Ro 31-7549 acetate,Bis VIII acetate	Apoptosis , PKC
	Bisindolylmaleimide VIII acetate (Ro 31-7549 acetate) is a potent and selective PKC inhibitor (IC50: 158 nM for rat brain PKC). It has IC50s of 53, 195, 163, 213, and 175 nM for PKC-α, PKC-βI, PKC-βII, PKC-γ, PKC-ε, resp...		Apoptosis , PKC
T80509	PKC 20-28,myristoylated	Myristoylated protein kinase C inhibitor 20-28	PKC
	Myristoylated protein kinase C inhibitor 20-28 (PKC 20-28,myristoylated) is a cell-permeable inhibitor of protein kinase C, utilized in cancer research [1].		PKC
TP1676	C-Reactive Protein (CRP) (201-206)	C-Reactive Protein (CRP) 201-206	Others
	C-Reactive Protein (CRP) Fragment (201-206) is a peptide segment derived from C-Reactive Protein (CRP), the quintessential indicator of inflammation. As a cardiovascular risk marker, CRP may facilitate atherogenesis.		Others
T6588	Mitoxantrone	mitozantrone	Topoisomerase , PKC
	Mitoxantrone (mitozantrone) is an anthracenedione antibiotic with antineoplastic activity. Mitoxantrone intercalates into and crosslinks DNA, thereby disrupting DNA and RNA replication. This agent also binds to topoisome...		Topoisomerase , PKC
T4185	Lavendustin C	HDBA,NSC 666251	CaMK , EGFR , Tyrosinase , Src
	lavendustin C (NSC 666251) is a potent inhibitor of epidermal growth factor (EGF) receptor-associated tyrosine kinase.		CaMK , EGFR , Tyrosinase , Src
T9317	TAK-041	NBI-1065846	GPR
	TAK-041 (NBI-1065846) is a potent and selective GPR139 agonist.		GPR
T17019	TCS 21311	NIBR3049	GSK-3 , JAK , PKC
	TCS 21311 (NIBR3049) is an effective and highly selective inhibitor of JAK3 (IC50: 8 nM). TCS 21311 inhibits PKCα, PKCθ, and GSK3β (IC50s: 13, 68, and 3 nM, respectively). It displays >100-fold selectivity over JAK1, JAK...		GSK-3 , JAK , PKC
T3689	Ruboxistaurin hydrochloride	Ruboxistaurin,LY333531 HCl,LY 333531 hydrochloride	PKC
	Ruboxistaurin hydrochloride (LY 333531 hydrochloride) is an Isozyme-selective inhibitor of protein kinase C (PKC); competitively and reversibly inhibits PKCβI and PKCβII (IC50 values are 4.7 and 5.9 nM respectively). Sel...		PKC
T1606	Fasudil	HA-1077,AT877	ROCK , Serine/threonin kinase , Calcium Channel , PKA , PKC , Autophagy
	Fasudil (HA-1077) is a potent inhibitor of ROCK1, PKA, PKC, and MLCK.
T9010	IMM-H007		Others , AMPK
	IMM-H007 is a novel lipid-lowering agent, increasing abca1 protein expression		Others , AMPK
T6513	Bisindolylmaleimide I	GF109203X,Go 6850	PDGFR , PKC
	Bisindolylmaleimide I (GF109203X) is a potent and highly selective protein kinase C (PKC) inhibitor with a Ki of 14 nM.		PDGFR , PKC
T6643	Ro 31-8220 Mesylate	Ro 31-8220 methanesulfonate,Bisindolylmaleimide IX,Bisindolylmaleimide IX mesylate	PKC
	Ro 31-8220 Mesylate (Bisindolylmaleimide IX mesylate) is a pan-PKC inhibitor for PKC-α/βI/βII/γ/ε (IC50: 5/24/14/27/24 nM), and also shows potent inhibition against MSK1, MAPKAP-K1b, S6K1, and GSK3β.		PKC
T2609	Masitinib	AB1010	Apoptosis , FAK , c-Fms , FGFR , Bcr-Abl , PDGFR , Src , c-Kit , Hck
	Masitinib (AB1010) is a tyrosine-kinase inhibitor used in the treatment of mast cell tumors in animals, specifically dogs. Since its introduction in November 2008 it has been distributed under the commercial name Masivet...
T3211	Midostaurin	N-Benzoylstaurosporine,PKC412,CGP41231,CGP 41251	Others , PKC
	PKC412(Midostaurin (PKC412); CGP41231; CGP41251) is a broad spectrum protein kinase inhibitor. Midostaurin inhibits protein kinase C alpha (PKCalpha), vascular endothelial growth factor receptor 2 (VEGFR2), c-kit, platel...		Others , PKC
T5423	PKC-theta inhibitor		PKC
	PKC-theta inhibitor is PKC-θinhibitor, with an IC50 of 12 nM.		PKC
T3060	Fasudil hydrochloride	Fasudil (HA-1077) HCl,HA-1077,Fasudil HCl,HA-1077 hydrochloride,AT-877	ROCK , Serine/threonin kinase , Calcium Channel , HIV Protease , PKA , PKC , Autophagy
	Fasudil hydrochloride (HA-1077) is a potent inhibitor of ROCK1, PKA, PKC, and MLCK with Ki of 0.33 μM, 1.0 μM, 9.3 μM and 55 μM, respectively.
T20168	Aurothiomalate sodium	Myocrisin,Myocrisine,Miochrysin,Sodium aurothiomalate,Myochrysine,gold sodium thiomalate	Others , PKC
	Sodium aurothiomalate is a gold compound that is used for its immunosuppressive anti-rheumatic effects. Aurothiomalate sodium (Miochrysin) is a potent and selective inhibitor of oncogenic PKC-ι signaling. Aurothiomalate ...		Others , PKC
T0158	Mitoxantrone dihydrochloride	Mitoxantrone 2HCl,Mitoxantrone hydrochloride,NSC-301739,mitozantrone dihydrochloride	Topoisomerase , PKC
	Mitoxantrone dihydrochloride (NSC-301739) is the hydrochloride salt of an anthracenedione antibiotic with antineoplastic activity. It is a type II topoisomerase inhibitor.		Topoisomerase , PKC
T21312	Afatinib	Afatinib free base,BIBW 2992	EGFR , Autophagy
	Afatinib (BIBW 2992) is an irreversible inhibitor of EGFR family (EGFR-wt, EGFR-L858R, EGFR-L858R/T790M and HER2 with IC50s of 0.5 nM, 0.4 nM, 10 nM and 14 nM , respectively).		EGFR , Autophagy
T1773	Afatinib Dimaleate	BIBW2992,Afatinib,BIBW 2992MA2,Afatinib (BIBW2992) Dimaleate	EGFR , HER , Autophagy
	Afatinib Dimaleate (BIBW 2992MA2) is an orally bioavailable anilino-quinazoline derivative and inhibitor of the receptor tyrosine kinase (RTK) epidermal growth factor receptor (ErbB; EGFR) family, with antineoplastic act...		EGFR , HER , Autophagy
T40101	(±)-1,2-Diolein	1,2-Dioleoyl-rac-glycerol	PKC
	(±)-1,2-Diolein (1,2-Dioleoyl-rac-glycerol) (1,2-Dioleoyl-rac-glycerol) is a PKC activator. (±)-1,2-Diolein could increases myotubes Ca 2+ influx.		PKC
T22831	Protein kinase inhibitor H-7 dihydrochloride	H-7 dihydrochloride	PKC
	Protein kinase inhibitor H-7 dihydrochloride(H-7 dihydrochloride) is a potent protein kinase C (PKC) inhibitor. Protein kinase inhibitor H-7 dihydrochloride (100 μM) significantly inhibits TPA (skin tumor promoter, 12-O-...		PKC

Compounds

Target: Histone Methyltransferase

PKC-iota inhibitor 1

Target: Myosin, PKA, PKC

Bisindolylmaleimide IV

T7659

Synonym:

Target: Others, PKC

Afuresertib hydrochloride

T7885

Synonym:

Target: ROCK, Akt, PKC

EX229

TQ0028

Synonym: Compound 991,C991

Target: AMPK

Afuresertib

T1911

Synonym: GSK2110183C,GSK2110183

Target: ROCK, Akt, PKC

CMPD101

T14989

Synonym:

Target: ROCK, GRK, PKC

Dorsomorphin

T1977

Synonym: Compound C,BML-275

Target: AMPK, Autophagy, TGF-beta/Smad

Target: Gap Junction Protein

Target: CaMK, Casein Kinase, PKA, PKC

Enzastaurin

T6280

Synonym: LY317615

Target: Apoptosis, PKC, Autophagy

Valrubicin

T7604

Synonym: Valstar,AD-32

Target: Antibiotic, PKC

R59949

T26019

Synonym: R-59949,R 59949

Target: Apoptosis, PKC

CGP60474

T14943

Synonym:

Target: VEGFR, CDK, PKC

Dorsomorphin dihydrochloride

T6146

Synonym: BML-275 2HCl,Compound C dihydrochloride,Dorsomorphin (Compound C) 2HCl,Compound C 2HCl,BML-275 dihydrochloride

Target: AMPK, Autophagy, TGF-beta/Smad

Delcasertib

T11740

Synonym: KAI-9803,BMS-875944

Target: PKC

N-Desmethyltamoxifen hydrochloride

T12148

Synonym:

Target: Estrogen Receptor/ERR, Endogenous Metabolite, PKC

Bisindolylmaleimide VIII acetate

T10549

Synonym: Ro 31-7549 acetate,Bis VIII acetate

Target: Apoptosis, PKC

PKC 20-28,myristoylated

T80509

Synonym: Myristoylated protein kinase C inhibitor 20-28

Target: PKC

C-Reactive Protein (CRP) (201-206)

TP1676

Synonym: C-Reactive Protein (CRP) 201-206

Target: Others

Mitoxantrone

T6588

Synonym: mitozantrone

Target: Topoisomerase, PKC

lavendustin C

T4185

Synonym: HDBA,NSC 666251

Target: CaMK, EGFR, Tyrosinase, Src

Target: GSK-3, JAK, PKC

Ruboxistaurin hydrochloride

T3689

Synonym: Ruboxistaurin,LY333531 HCl,LY 333531 hydrochloride

Target: PKC

Fasudil

T1606

Synonym: HA-1077,AT877

Target: ROCK, Serine/threonin kinase, Calcium Channel, PKA, PKC, Autophagy

Bisindolylmaleimide I

T6513

Synonym: GF109203X,Go 6850

Target: PDGFR, PKC

Ro 31-8220 Mesylate

T6643

Synonym: Ro 31-8220 methanesulfonate,Bisindolylmaleimide IX,Bisindolylmaleimide IX mesylate

Target: Apoptosis, FAK, c-Fms, FGFR, Bcr-Abl, PDGFR, Src, c-Kit, Hck

Midostaurin

T3211

Synonym: N-Benzoylstaurosporine,PKC412,CGP41231,CGP 41251

Target: Others, PKC

PKC-theta inhibitor

T5423

Synonym:

Target: PKC

Fasudil hydrochloride

T3060

Synonym: Fasudil (HA-1077) HCl,HA-1077,Fasudil HCl,HA-1077 hydrochloride,AT-877

Target: ROCK, Serine/threonin kinase, Calcium Channel, HIV Protease, PKA, PKC, Autophagy

Aurothiomalate sodium

T20168

Synonym: Myocrisin,Myocrisine,Miochrysin,Sodium aurothiomalate,Myochrysine,gold sodium thiomalate

Target: Others, PKC

Mitoxantrone dihydrochloride

T0158

Synonym: Mitoxantrone 2HCl,Mitoxantrone hydrochloride,NSC-301739,mitozantrone dihydrochloride

Target: Topoisomerase, PKC

Afatinib

T21312

Synonym: Afatinib free base,BIBW 2992

Target: EGFR, Autophagy

Afatinib Dimaleate

T1773

Synonym: BIBW2992,Afatinib,BIBW 2992MA2,Afatinib (BIBW2992) Dimaleate

Target: EGFR, HER, Autophagy

(±)-1,2-Diolein

T40101

Synonym: 1,2-Dioleoyl-rac-glycerol

Target: PKC

Protein kinase inhibitor H-7 dihydrochloride

T22831

Synonym: H-7 dihydrochloride

Target: PKC

Cat No.	Product Name	Synonyms	Targets
TN1557	Decursinol angelate		ERK , VEGFR , PKC , JNK
	Decursinol angelate has anti-tumor, anti-inflammatory, anti-oxidant, and hepatoprotective activities, it inhibits VEGF-induced angiogenesis via suppression of the VEGFR-2-signaling pathway; it also suppresses invasion an...		ERK , VEGFR , PKC , JNK
T5771	Hypocrellin A		Antibacterial , PKC , Parasite
	Hypocrellin A is PKC inhibitor, has light-induced antitumor,antifungal and antiviral activities, it also exerts immunomodulatory effects on MHC-restricted presentation of antigen.		Antibacterial , PKC , Parasite
T2750	Ginkgolide C	BN-52022	MMP , Sirtuin , Endogenous Metabolite , AMPK
	Ginkgolide C (BN-52022), a natural product, can enhance the cardiac function of rats in the body.		MMP , Sirtuin , Endogenous Metabolite , AMPK
T5S2017	Ingenol	(-)-Ingenol	PKC
	1. Ingenol ((-)-Ingenol) mebutate is an effective treatment for actinic keratosis. 2. Formulating novel derivatives from Ingenol esters may be an innovative approach to develop new lead compounds to reactivate latent HIV...		PKC
T4S1335	Daphnoretin	Dephnoretin,Thymelol	Influenza Virus , Caspase , PKC
	1. Daphnoretin (Thymelol) has strong antiviral activity, mainly on the later phase of the replication cycle. 2. Daphnoretin has anticancer effects on leukemia, osteosarcoma and uterine cervix cancer cells, might through ...		Influenza Virus , Caspase , PKC
TN1499	Cimiracemoside C	Cimicifugoside M	AMPK
	Cimiracemoside C (Cimicifugoside M) is an active component of Cimicifuga racemosa. It activates AMPK and has the potential activity against diabetes.		AMPK
T6S0052	Chelerythrine	Toddalin,Broussonpapyrine,Cheleritrine	Apoptosis , BCL , PKC , Autophagy
	1. Chelerythrine (Broussonpapyrine) may have antimanic effect . 2. Chelerythrine can inhibit telomerase activity. 3. Chelerythrine is a well-known protein kinase C inhibitor . 4. Chelerythrine has potential antiprolifera...		Apoptosis , BCL , PKC , Autophagy
T3419	Chelerythrine chloride		Apoptosis , BCL , PKC , Autophagy
	Chelerythrine Chloride is a cell-permeable inhibitor of protein kinase C, competitive with respect to the phosphate acceptor and non-competitive with respect to ATP.		Apoptosis , BCL , PKC , Autophagy
T5552	Methyl cinnamate		Tyrosinase , Antibacterial , AMPK
	Methyl cinnamate, a tyrosinase inhibitor and a flavoring compound, has antimicrobial, antiadipogenic, vasorelaxant, and anti-inflammatory effects.		Tyrosinase , Antibacterial , AMPK
T22464	1,2-Dimyristoyl-sn-glycerol	1,2-DMG	Others , PKC
	1,2-Dimyristoyl-sn-glycerol (1,2-DMG) is able to increase AChE activity by 35-40% at concentrations of 25 micrograms/ml in the parasite S. mansoni..		Others , PKC
T2851	Daphnetin	7,8-Dihydroxycoumarin,Daphnetol	EGFR , PKA , PKC , Parasite , Autophagy
	Daphnetin (7,8-Dihydroxycoumarin), a natural coumarin derivative, is a protein kinase inhibitor with inhibitory for EGFR (IC50: 7.67 μM), PKA (IC50: 9.33 μM), and PKC (IC50: 25.01 μM), also exhibit anti-oxidant and anti-...		EGFR , PKA , PKC , Parasite , Autophagy
T13265	Urolithin B		ERK , NF-κB , Akt , Endogenous Metabolite , JNK , AMPK
	Urolithin B is one of the gut microbial metabolites of ellagitannins and is found in diverse plant foods, including pomegranates, berries, walnuts, tropical fruits, and medicinal herbs. Urolithin B inhibits NF-κB activit...		ERK , NF-κB , Akt , Endogenous Metabolite , JNK , AMPK
T3001	Honokiol	NSC 293100	ERK , HCV Protease , MEK , Akt , Autophagy
	Honokiol (NSC-293100) is the active principle of magnolia extract. It inhibits the activation of Akt and enhances the phosphorylation of ERK1/ERK2.		ERK , HCV Protease , MEK , Akt , Autophagy
T3375	Verbascoside	Kusaginin,Acteoside,TJC160	Apoptosis , PARP , Antibacterial , PKC , p53 , HSV
	Verbascoside (Kusaginin) is a protein kinase C inhibitor with antimicrobial, anti-inflammatory activities.		Apoptosis , PARP , Antibacterial , PKC , p53 , HSV
TN1136	Procyanidin A1	Proanthocyanidin A1	LDL , Calcium Channel , PKC
	Procyanidin A1 (Proanthocyanidin A1) has antiallergic effects, it inhibits degranulation downstream of protein kinase C activation or Ca2+; influx from an internal store in RBL-2H3 cells.		LDL , Calcium Channel , PKC
T3S1416	Decursin	Decursinol angelate,(+)-Decursin	Apoptosis , PKC
	1. Decursin (Decursinol angelate) is able to attenuate kainic acid-induced seizures and could have potential as an antiepileptic drug. 2. Decursin exhibits hepatoprotective effects , potentially by inhibiting the TGF-β1 ...		Apoptosis , PKC
T7792	Hispidin		Endogenous Metabolite , PKC
	Hispidin is a polyphenol originally, including antioxidant, anti-inflammatory, and cytoprotective properties		Endogenous Metabolite , PKC
T0392	Artemisinin	Qinghaosu,Artemisinine,Qinghaosu,NSC 369397,Artemisinine	HCV Protease , Ferroptosis , Akt , Parasite
	Artemisinin (Qinghaosu) is an ancient Chinese herbal therapy for malarial fevers which has been recently found to have potent activity against many forms of malarial organisms, including chloroquine-resistant Plasmodium ...		HCV Protease , Ferroptosis , Akt , Parasite
T9605	Sangivamycin	BA-90912,NSC 65346	Nucleoside Antimetabolite/Analog , PKC
	Sangivamycin (NSC-65346) is an effective inhibitor of protein kinase C (PKC, Ki = 10 μM). Sangivamycin exhibits antiproliferative activity against a variety of human cancers.		Nucleoside Antimetabolite/Analog , PKC
T5891	D-ERYTHRO-SPHINGOSINE	trans-4-Sphingenine,erythro-C18-Sphingosine,Erythrosphingosine	Phosphatase , Endogenous Metabolite , PKC
	D-erythro-Sphingosine (trans-4-Sphingenine) is a protein kinase C (PKC) inhibitor. D-erythro-Sphingosine (Erythrosphingosine) is also a PP2A activator		Phosphatase , Endogenous Metabolite , PKC
T6680	Staurosporine	Antibiotic AM-2282,AM-2282,CGP 41251	Apoptosis , PKA , Antibacterial , Antibiotic , Src , PKC , Antifungal
	Staurosporine (AM-2282) is a protein kinase inhibitor with ATP-competitive and non-selective inhibitory activity (IC50=6/15/2/3/3000 nM) against PKC, PKA, c-Fgr, phosphorylase kinase and TAOK2. Staurosporine also induces...
T11665	Ionomycin calcium	SQ23377 calcium	Apoptosis , Calcium Channel , Antibacterial , Antibiotic , PKC
	lonomycin calcium is a potent, selective calcium ionophore and an antibiotic produced by Streptomyces conglobatus. also induces the activation of protein kinase C (PKC). Ionomycin calcium (SQ23377 calcium) is highly spec...
TN1299	Desmethylglycitein	6,7,4'-Trihydroxyisoflavone	PI3K , CDK , PKC
	Desmethylglycitein (6,7,4'-Trihydroxyisoflavone) , is a novel inhibitor of PKCα in suppressing solar UV-induced matrix metalloproteinase 1, which has antioxidant, and anti-cancer activities.		PI3K , CDK , PKC
T16791	Rottlerin	Mallotoxin,NSC 56346,NSC 94525	CaMK , Apoptosis , Others , HIV Protease , PKA , PKC , Autophagy
	Rottlerin (NSC-56346) is a natural product purified from Mallotus Philippinensis and is a specific PKC inhibitor (IC50: PKCδ of 3-6 μM, PKCα,β,γ of 30-42 μM, PKCε,η,ζ of 80-100 μM). Rottlerin causes apoptosis via caspase...
T15355	Fumitremorgin C	12α-Fumitremorgin C	BCRP , Antibacterial , Antibiotic , ABC
	Fumitremorgin C (12α-Fumitremorgin C) is a mycotoxin and inhibits ABCG2/BRCP.		BCRP , Antibacterial , Antibiotic , ABC
TQ0198	Phorbol 12-myristate 13-acetate	PMA	NF-κB , S1P Receptor , PKC
	Phorbol 12-myristate 13-acetate (PMA) belongs to the phorbol ester group of natural products and is an activator of PKC, SphK, and NF-κB. Phorbol 12-myristate 13-acetate induces THP1 cell differentiation.		NF-κB , S1P Receptor , PKC
T6S0923	Hypericin	Hypericine,Cyclosan	Apoptosis , Antiviral , Influenza Virus , Tyrosine Kinases , Antibacterial , PKC
	1. Hypericin (Cyclosan) has antineoplastic activity. 2. Hypericin has antibiotic and antiviral activities. 3. Hypericin has antidepressive activity through inhibiting monoamine oxidase enzyme. 4. Hypericin inhibits RANKL...
TN1034	Sennidin B		HCV Protease , transporter , Akt , PI3K
	Sennidin B stimulates glucose incorporation in rat adipocytes.		HCV Protease , transporter , Akt , PI3K
TN1033	Sennidin A		HCV Protease , transporter , Akt , PI3K
	Sennidin A, has two hydroxyanthraquinone-like moieties, exerts inhibition on NS3 helicase with IC50 values of 0.8 μM.		HCV Protease , transporter , Akt , PI3K
T5736	1,3-Dicaffeoylquinic acid	CYNARIN,Cyclohexanecarboxylic acid, 1,3-bis[[3-(3,4-dihydroxyphenyl)-1-oxo-2-propen-1-yl]oxy]-4,5-dihydroxy-, (1S,3R,4R,5R)-,1,3-O-Dicaffeoylquinic acid,1,5-Dicaffeoylquinic acid	Reactive Oxygen Species , Akt , PI3K
	1,3-Dicaffeoylquinic acid (CYNARIN) is a natural product. It shows antioxidant and choleretic properties and is a potential immunosuppressive agent.		Reactive Oxygen Species , Akt , PI3K
TN1448	(-)-Bornyl acetate	L-(-)-Bornyl acetate,Bornyl acetate	p38 MAPK , NF-κB , JNK , Antifungal
	(-)-Bornyl acetate (L-(-)-Bornyl acetate) is a less active enantiomer of (+)-Bornyl acetate. (-)-Bornyl acetate isolates from hyssop oil and possesses antifungal activity. (-)-Bornyl acetate shows highly active whitening...		p38 MAPK , NF-κB , JNK , Antifungal
T22723	Dihydrosphingosine		Others
	Dihydrosphingosine is a Protein kinase C inhibitor.		Others
T23772	Balanol	Ophiocordin,BA1,Azepinostatin,(-)-Balanol,(3R-trans)-Balanol
	Balanol is an ATP-competitive Protein Kinase C and Protein Kinase A inhibitor.
T17198	UCN-02	7-epi-Hydroxystaurosporine	Others
	UCN-02 is a selective protein kinase C inhibitor produced by Streptomyces strain N-12 (IC50s: 62 nM and 250 nM for PKC and protein kinase A (PKA), respectively).		Others
T75565	Vanicoside A
	Vanicoside A is a protein kinase C( PKC ) inhibitor from Polygonum pensylvanicum [1] .
TN3809	Dehydrojuncusol		HCV Protease
	Dehydrojuncusol, a new inhibitor of hepatitis C virus RNA replication, it inhibits infection of different HCV genotypes by targeting the NS5A protein and is active against resistant HCV variants frequently found in patie...		HCV Protease
T15637	K-252b		PKC
	K-252b, an indolocarbazole derived from the actinomycete Nocardiopsis, functions as a protein kinase C (PKC) inhibitor. It is effective in inhibiting extracellular kinases in cultured cells due to its inability to freely...		PKC
T68802	Vibsanin A
	Vibsanin A, an activator of protein kinase C (PKC) and an inhibitor of HSP90, demonstrates anti-proliferative effects on human cancer cell lines.
TMA1743	Ergosterol peroxide		ERK , VEGFR , p38 MAPK , Wnt/beta-catenin , Akt , JAK , CDK , JNK , STAT , Antifection
	Ergosterol peroxide is an inhibitor of osteoclast differentiation, which has antiviral, trypanocidal, antitumor, and antiangiogenic actions, it can stimulate Foxo3a activity by inhibiting pAKT and c-Myc and activating pr...
TN1663	Ganoderic acid DM		PARP , Androgen Receptor , CDK
	Ganoderic acid DM is an antiandrogenic osteoclastogenesis inhibitor, it especially suppresses the expression of c-Fos and nuclear factor of activated T cells c1 (NFATc1), this suppression leads to the inhibition of dendr...		PARP , Androgen Receptor , CDK
TN4300	Isojacareubin		MAPK , PKC , Antifection
	Isojacareubin displays potent activity against H. pylori HP40 clinical isolate with MIC 23.9 uM, which is approximately two times greater than that of the standard drug amoxicillin. Isojacareubin is a potent inhibitor of...		MAPK , PKC , Antifection
T75491	3-(2-Hydroxyethyl) thio withaferin A
	3-(2-Hydroxyethyl) thio withaferin A, a derivative of Withaferin A, is a steroidal lactone that inhibits NF-kB activation and targets vimentin, showcasing potent anti-inflammatory and anticancer properties. It also acts ...
T36295	Echistatin TFA
	Echistatin TFA, the smallest active RGD protein belonging to the family of disintegrins that are derived from snake venoms, is a potent inhibitor of platelet aggregation. Echistatin is a potent inhibitor of bone resorpti...
T35577	Phosphatidylserines (bovine)
	Phosphatidylserine is a naturally occurring phospholipid that comprises 2-10% of total phospholipids in mammals and is enriched in the central nervous system, particularly the retina. It is anionic and found mainly on th...
T38069	Aquastatin A
	Aquastatin A is a fungal metabolite originally isolated fromF. aquaeductuumthat has diverse biological activities.1It is active againstS. aureus(MIC = 32 μg/ml) and inhibits enoyl-acyl carrier protein reductase (Fabl; IC...

Natural Products

Decursinol angelate

TN1557

Synonym:

Target: ERK, VEGFR, PKC, JNK

Hypocrellin A

T5771

Synonym:

Target: Antibacterial, PKC, Parasite

Ginkgolide C

T2750

Synonym: BN-52022

Target: MMP, Sirtuin, Endogenous Metabolite, AMPK

Synonym: Dephnoretin,Thymelol

Target: Influenza Virus, Caspase, PKC

Cimiracemoside C

TN1499

Synonym: Cimicifugoside M

Target: AMPK

Chelerythrine

T6S0052

Synonym: Toddalin,Broussonpapyrine,Cheleritrine

Target: Apoptosis, BCL, PKC, Autophagy

Chelerythrine chloride

T3419

Synonym:

Target: Apoptosis, BCL, PKC, Autophagy

Methyl cinnamate

T5552

Synonym:

Target: Tyrosinase, Antibacterial, AMPK

1,2-Dimyristoyl-sn-glycerol

Synonym: 7,8-Dihydroxycoumarin,Daphnetol

Target: EGFR, PKA, PKC, Parasite, Autophagy

Urolithin B

T13265

Synonym:

Target: ERK, NF-κB, Akt, Endogenous Metabolite, JNK, AMPK

Honokiol

T3001

Synonym: NSC 293100

Target: ERK, HCV Protease, MEK, Akt, Autophagy

Verbascoside

T3375

Synonym: Kusaginin,Acteoside,TJC160

Target: Apoptosis, PARP, Antibacterial, PKC, p53, HSV

Procyanidin A1

TN1136

Synonym: Proanthocyanidin A1

Target: LDL, Calcium Channel, PKC

Decursin

T3S1416

Synonym: Decursinol angelate,(+)-Decursin

Target: Apoptosis, PKC

Hispidin

T7792

Synonym:

Target: Endogenous Metabolite, PKC

Artemisinin

T0392

Synonym: Qinghaosu,Artemisinine,Qinghaosu,NSC 369397,Artemisinine

Target: HCV Protease, Ferroptosis, Akt, Parasite

Sangivamycin

T9605

Synonym: BA-90912,NSC 65346

Target: Nucleoside Antimetabolite/Analog, PKC

D-ERYTHRO-SPHINGOSINE

T5891

Synonym: trans-4-Sphingenine,erythro-C18-Sphingosine,Erythrosphingosine

Target: Phosphatase, Endogenous Metabolite, PKC

Staurosporine

T6680

Synonym: Antibiotic AM-2282,AM-2282,CGP 41251

Target: Apoptosis, PKA, Antibacterial, Antibiotic, Src, PKC, Antifungal

Ionomycin calcium

T11665

Synonym: SQ23377 calcium

Target: Apoptosis, Calcium Channel, Antibacterial, Antibiotic, PKC

Desmethylglycitein

TN1299

Synonym: 6,7,4'-Trihydroxyisoflavone

Target: PI3K, CDK, PKC

Rottlerin

T16791

Synonym: Mallotoxin,NSC 56346,NSC 94525

Target: CaMK, Apoptosis, Others, HIV Protease, PKA, PKC, Autophagy

Fumitremorgin C

T15355

Synonym: 12α-Fumitremorgin C

Target: BCRP, Antibacterial, Antibiotic, ABC

Phorbol 12-myristate 13-acetate

TQ0198

Synonym: PMA

Target: NF-κB, S1P Receptor, PKC

Hypericin

T6S0923

Synonym: Hypericine,Cyclosan

Target: Apoptosis, Antiviral, Influenza Virus, Tyrosine Kinases, Antibacterial, PKC

Sennidin B

TN1034

Synonym:

Target: HCV Protease, transporter, Akt, PI3K

Sennidin A

TN1033

Synonym:

Target: HCV Protease, transporter, Akt, PI3K

1,3-Dicaffeoylquinic acid

T5736

Synonym: CYNARIN,Cyclohexanecarboxylic acid, 1,3-bis[[3-(3,4-dihydroxyphenyl)-1-oxo-2-propen-1-yl]oxy]-4,5-dihydroxy-, (1S,3R,4R,5R)-,1,3-O-Dicaffeoylquinic acid,1,5-Dicaffeoylquinic acid

Target: Reactive Oxygen Species, Akt, PI3K

(-)-Bornyl acetate

TN1448

Synonym: L-(-)-Bornyl acetate,Bornyl acetate

Target: p38 MAPK, NF-κB, JNK, Antifungal

Synonym: Ophiocordin,BA1,Azepinostatin,(-)-Balanol,(3R-trans)-Balanol

Target:

UCN-02

T17198

Synonym: 7-epi-Hydroxystaurosporine

Target: ERK, VEGFR, p38 MAPK, Wnt/beta-catenin, Akt, JAK, CDK, JNK, STAT, Antifection

Ganoderic acid DM

TN1663

Synonym:

Target: PARP, Androgen Receptor, CDK

Isojacareubin

TN4300

Synonym:

Target: MAPK, PKC, Antifection

3-(2-Hydroxyethyl) thio withaferin A

Phosphatidylserines (bovine)

Recombinant Proteins

Species：

Expression System：

Tag：

Cat No.	Product Name	Species	Expression System
TMPH-02472	14-3-3 beta/alpha Protein, Mouse, Recombinant (His)	Mouse	P. pastoris (Yeast)
	14-3-3 beta/alpha Protein, Mouse, Recombinant (His) is expressed in yeast with N-6xHis tag. The predicted molecular weight is 30.1 kDa and the accession number is Q9CQV8.
TMPH-02471	14-3-3 beta/alpha Protein, Mouse, Recombinant (E. coli, His)	Mouse	E. coli
	14-3-3 beta/alpha Protein, Mouse, Recombinant (E. coli, His) is expressed in E. coli expression system with N-10xHis tag. The predicted molecular weight is 33.6 kDa and the accession number is Q9CQV8.
TMPH-02473	14-3-3 zeta/delta Protein, Mouse, Recombinant (His & SUMO)	Mouse	E. coli
	Adapter protein implicated in the regulation of a large spectrum of both general and specialized signaling pathways. Binds to a large number of partners, usually by recognition of a phosphoserine or phosphothreonine moti...
TMPJ-01261	PPP1R14A Protein, Human, Recombinant (His)	Human	E. coli
	Protein Phosphatase 1 Regulatory Subunit 14A (PPP1R14A) belongs to the PP1 inhibitor family. PPP1R14A is mapped to chromosome 19q13.13-q13.2. PPP1R14A binds directly to protein kinase C and casein kinase I. Meantime, PPP...
TMPJ-00490	Serpin A5 Protein, Human, Recombinant (His)	Human	HEK293 Cells
	Serpin A5 is a member of the human Serpin superfamily consists of at least 35 members. It is synthesized in the liver and has been detected in saliva, cerebral spinal fluid, amniotic fluid, tears and semen. As a potent i...
TMPH-00478	DIT33 Protein, Dirofilaria immitis, Recombinant (His & Myc)	Dirofilaria immitis	E. coli
	Aspartyl protease inhibitor. DIT33 Protein, Dirofilaria immitis, Recombinant (His & Myc) is expressed in E. coli expression system with N-10xHis and C-Myc tag. The predicted molecular weight is 32.0 kDa and the accession...
TMPH-00155	Barstar Protein, Bacillus amyloliquefaciens, Recombinant (His & Myc)	Bacillus amyloliquefaciens	E. coli
	Inhibitor of the ribonuclease barnase. Forms a one-to-one non-covalent complex. Barstar Protein, Bacillus amyloliquefaciens, Recombinant (His & Myc) is expressed in E. coli expression system with N-10xHis and C-Myc tag. ...
TMPH-02437	5T4/TPBG Protein, Cynomolgus, Recombinant (His & Myc)	Cynomolgus	HEK293 Cells
	May function as an inhibitor of Wnt/beta-catenin signaling by indirectly interacting with LRP6 and blocking Wnt3a-dependent LRP6 internalization. 5T4/TPBG Protein, Cynomolgus, Recombinant (His & Myc) is expressed in HEK2...
TMPJ-01032	SPINK7 Protein, Human, Recombinant (His)	Human	HEK293 Cells
	Serine protease inhibitor Kazal-type 7(SPINK7) is a secreted protein, that in humans is encoded by the SPINK7 gene. SPINK7 contains 1 Kazal-like domain. SPINK7 is probably serine protease inhibitor. Recombinant human SPI...
TMPJ-00625	Serpin E1 Protein, Mouse, Recombinant (His)	Mouse	HEK293 Cells
	Plasminogen activator inhibitor-1 (serpin E1) is a serine protease inhibitor which belongs to the serpin family. Serpin E1 acts as 'bait' for tissue plasminogen activator, urokinase, protein C and matriptase-3/TMPRSS7. I...
TMPH-02436	5T4/TPBG Protein, Cynomolgus, Recombinant (E. coli, His & Myc)	Cynomolgus	E. coli
	May function as an inhibitor of Wnt/beta-catenin signaling by indirectly interacting with LRP6 and blocking Wnt3a-dependent LRP6 internalization. 5T4/TPBG Protein, Cynomolgus, Recombinant (E. coli, His & Myc) is expresse...
TMPK-00194	TFPI Protein, Human, Recombinant (His & Avi)	Human	HEK293 Cells
	Oestrogens influence the pathophysiology and development of hormone-sensitive cancers, such as breast cancer. Tissue factor pathway inhibitor (TFPI) is a serine protease inhibitor of the extrinsic coagulation pathway and...
TMPJ-00873	CCL3L1 Protein, Human, Recombinant (His)	Human	HEK293 Cells
	C-C Motif Chemokine 3-Like 1 (CCL3L1) is a secreted protein that belongs to the intercrine beta (chemokine CC) family. CCL3L1 is a ligand for CCR1, CCR3 and CCR5. CCL3L1 binds to several chemokine receptors including che...
TMPY-01203	RP2 Protein, Human, Recombinant (GST)	Human	Baculovirus Insect Cells
	XRP2, also known as Protein XRP2 and RP2, is a member of the TBCC (tubulin cofactor C) family and contains one C-CAP/cofactor C-like domain. This protein is encoded by the RP2 gene in humans. XRP2 stimulates the GTPase a...
TMPK-00195	TFPI Protein, Human, Recombinant (His & Avi), Biotinylated	Human	HEK293 Cells
	Oestrogens influence the pathophysiology and development of hormone-sensitive cancers, such as breast cancer. Tissue factor pathway inhibitor (TFPI) is a serine protease inhibitor of the extrinsic coagulation pathway and...
TMPJ-00044	TNNC1 Protein, Human, Recombinant (His)	Human	E. coli
	Troponin I, also known as TNI, is a 24 kDa component of a protein complex on striated muscle thin filaments.Troponin is the central regulatory protein of striated muscle contraction. Tn consists of three components: Tn-I...
TMPH-02440	GHR Protein, Rhesus macaque, Recombinant (His)	Rhesus	E. coli
	Receptor for pituitary gland growth hormone involved in regulating postnatal body growth. On ligand binding, couples to, and activates the JAK2/STAT5 pathway.; The soluble form (GHBP) acts as a reservoir of growth hormon...
TMPK-01204	TNFRSF19 Protein, Human, Recombinant (His)	Human	HEK293 Cells
	A novel susceptibility gene TNFRSF19, which encodes an orphan member of the TNF receptor superfamily known to be associated with nasopharyngeal carcinoma (NPC) and lung cancer risk. TNFRSF19, a susceptibility gene for na...
TMPY-02128	Serpin B1 Protein, Human, Recombinant (His)	Human	Baculovirus Insect Cells
	SerpinB1 is an endogenous inhibitor of serine proteases recognized for its anti-inflammatory and host-protective properties. Serum SerpinB1 levels are elevated in patients with type 2 diabetes compared with that in healt...
TMPH-02757	LILRB3 Protein, Mouse, Recombinant (aa 25-642, His)	Mouse	HEK293 Cells
	May act as receptor for class I MHC antigens. Becomes activated upon coligation of LILRB3 and immune receptors, such as FCGR2B and the B-cell receptor. Down-regulates antigen-induced B-cell activation by recruiting phosp...
TMPH-03204	GHR Protein, Rabbit, Recombinant (His & Myc)	Rabbit	E. coli
	Receptor for pituitary gland growth hormone involved in regulating postnatal body growth. On ligand binding, couples to, and activates the JAK2/STAT5 pathway.; The soluble form (GHBP) acts as a reservoir of growth hormon...
TMPK-01203	TNFRSF19 Protein, Human, Recombinant (hFc)	Human	HEK293 Cells
	A novel susceptibility gene TNFRSF19, which encodes an orphan member of the TNF receptor superfamily known to be associated with nasopharyngeal carcinoma (NPC) and lung cancer risk. TNFRSF19, a susceptibility gene for na...
TMPH-03112	GHR Protein, Pig, Recombinant (His)	Sus scrofa (Pig)	E. coli
	Receptor for pituitary gland growth hormone involved in regulating postnatal body growth. On ligand binding, couples to, and activates the JAK2/STAT5 pathway.; The soluble form (GHBP) acts as a reservoir of growth hormon...
TMPH-02898	SPINK2 Protein, Mouse, Recombinant (His & Myc)	Mouse	E. coli
	As a strong inhibitor of acrosin, it is required for normal spermiogenesis. It probably hinders premature activation of proacrosin and other proteases, thus preventing the cascade of events leading to spermiogenesis defe...
TMPY-02595	DUSP14 Protein, Human, Recombinant (His & MBP)	Human	E. coli
	Dual specific phosphatase 14 / MAP-kinase phophatase-6 (DUSP14 / MKP6) is a member of Dual-specificity phosphatases that is a subclass of protein tyrosine phosphatases (PTP) families that can dephosphorylate bothe phosph...
TMPH-01335	FGF-5 Protein, Human, Recombinant (GST & His & Myc)	Human	E. coli
	Plays an important role in the regulation of cell proliferation and cell differentiation. Required for normal regulation of the hair growth cycle. Functions as an inhibitor of hair elongation by promoting progression fro...
TMPJ-00857	Thrombomodulin Protein, Mouse, Recombinant (His)	Mouse	HEK293 Cells
	Thrombomodulin is also known as CD141 antigen and blood dendritic cell antigen 3 (BDCA3), which is encoded by the THBD gene. The deduced amino acid sequence of mouse THBD predicts a signal peptide (aa 1 to 16) and a matu...
TMPK-00924	SLPI Protein, Mouse, Recombinant (hFc)	Mouse	HEK293 Cells
	Elafin and SLPI (secretory leucocyte protease inhibitor) have multiple important roles both in normal homoeostasis and at sites of inflammation. These include antiprotease and antimicrobial activity as well as modulation...
TMPH-03684	Varicella-zoster virus (strain Dumas) glycoprotein L/gL Protein (His & Myc)	HHV-3	E. coli
	The heterodimer glycoprotein H-glycoprotein L is required for the fusion of viral and plasma membranes leading to virus entry into the host cell. Acts as a functional inhibitor of gH and maintains gH in an inhibited form...
TMPH-03685	Varicella-zoster virus (strain Oka vaccine) glycoprotein L/gL Protein (His & Myc)	HHV-3	E. coli
	The heterodimer glycoprotein H-glycoprotein L is required for the fusion of viral and plasma membranes leading to virus entry into the host cell. Acts as a functional inhibitor of gH and maintains gH in an inhibited form...
TMPK-00767	SLPI Protein, Human, Recombinant (hFc)	Human	HEK293 Cells
	Elafin and SLPI (secretory leucocyte protease inhibitor) have multiple important roles both in normal homoeostasis and at sites of inflammation. These include antiprotease and antimicrobial activity as well as modulation...
TMPH-03559	Sbi Protein, S. aureus, Recombinant (Avi & His & MBP), Biotinylated	Staphylococcus aureus	E. coli
	Plays a role in the inhibition of both the innate and adaptive immune responses. Possesses two N-terminal domains that bind the Fc region of IgG and two domains that form a tripartite complex with complement factors C3b ...
TMPH-00227	Beta-casein Protein, Bovine, Recombinant (His & Myc)	Bovine	E. coli
	Important role in determination of the surface properties of the casein micelles.; Casoparan acts as a macrophage activator, increasing the phagocytic activity of macrophages and peroxide release from macrophages. It als...
TMPY-04550	JNK2 Protein, Human, Recombinant (His)	Human	Baculovirus Insect Cells
	Mitogen-activated protein kinase 9 (MAPK9), also well known as c-Jun N-terminal kinase (JNK2), is a member of the MAP kinase subfamily belonging to the protein kinase superfamily. MAPK9 responds to activation by environm...
TMPY-04100	MMP-26 Protein, Human, Recombinant	Human	E. coli
	MMP26 (Matrix Metallopeptidase 26) is a Protein Coding gene. MMP26 is a member of matrix metalloproteinases (MMPs) and has been reported to be highly expressed in many cancers. The protein differs from most MMP family me...
TMPY-03413	PPIL2 Protein, Human, Recombinant (aa 280-457, His)	Human	E. coli
	PPIL2, is an enzyme that belongs to the cyclophilin family. The cyclophilins are peptidylprolyl isomerases and are highly conserved ubiquitous. They play an important role in protein folding, immunosuppression by cyclosp...
TMPJ-00963	CDKN2C Protein, Human, Recombinant (His)	Human	E. coli
	Cyclin-Dependent Kinase 4 Inhibitor C (CDKN2C) is a member of the INK4 family of cyclin dependent kinase inhibitors. CDKN2C contains 4 ANK repeats and interacts with CDK4 or CDK6. Highest levels of CDKN2C can be found in...
TMPH-02832	Serpin A5 Protein, Mouse, Recombinant (His)	Mouse	Baculovirus Insect Cells
	Heparin-dependent serine protease inhibitor acting in body fluids and secretions. Inactivates serine proteases by binding irreversibly to their serine activation site. Involved in the regulation of intravascular and extr...
TMPJ-00072	IL-18BPd Protein, Mouse, Recombinant (hFc)	Mouse	HEK293 Cells
	Interleukin 18 binding protein (IL-18BP) is a physiological inhibitor that acts through binding to the receptor-binding site of IL-18. IL-18 stimulates INF-γ, which then stimulates 18BP production via NF-κB. The interact...
TMPJ-00891	Kallikrein 2/KLK2 Protein, Human, Recombinant (His)	Human	HEK293 Cells
	Kallikrein-2 (KLK2) is a secreted serine protease that belongs to the peptidase S1 family of Kallikrein subfamily. KLK2 contains 1 peptidase S1 domain. It is highly expressed in the human prostate gland. KLK2 can cleave ...
TMPY-02014	Coagulation factor VII/F7 Protein, Human, Recombinant (His)	Human	HEK293 Cells
	Coagulation factor VII, also known as Serum prothrombin conversion accelerator, Factor VII, F7 and FVII, is a member of the peptidase S1 family. Factor VII is one of the central proteins in the coagulation cascade. It is...
TMPJ-00502	Serpin G1 Protein, Human, Recombinant (His)	Human	HEK293 Cells
	As protease inhibitors, serpins have an array of functions including regulating blood clotting, the complement pathway, extracellular matrix remodeling, and cell motility. Serpin G1 is a serine protease inhibitor protein...
TMPJ-00472	Vitronectin Protein, Human, Recombinant (Truncated, His)	Human	HEK293 Cells
	Vitronectin, also known as VTN, is a large glycoprotein found in blood and the extracellular matrix (ECM). Vitronectin is a plasma glycoprotein implicated as a regulator of diverse physiological process, including blood ...
TMPJ-01166	IGFBP-7 Protein, Mouse, Recombinant (His)	Mouse	HEK293 Cells
	Insulin-like growth factor-binding protein 7(IGFBP-7) is a secreted glycosylated protein that contains three protein domain modules. IGFBP7 contains an N-terminal IGFBP domain, followed by a Kazal-type serine proteinase ...
TMPY-02070	Cystatin SN Protein, Human, Recombinant (His)	Human	HEK293 Cells
	Cystatin-SN, also known as Cystain-SA-I, Cystatin-1, Salivary cystatin-SA-1 and CST1, is a secreted protein which belongs to thecystatin family. The cystatin superfamily encompasses proteins that contain multiple cyst...
TMPY-00741	CXCL4 Protein, Human, Recombinant	Human	E. coli
	Platelet factor 4 (PF4), also known as chemokine (C-X-C motif) ligand 4 (CXCL4), is a small cytokine belonging to the CXC chemokine family. CXCL4/PF4 is released from the alpha-granules of activated platelets and binds w...
TMPY-02001	RTN4 Protein, Human, Recombinant (GST)	Human	E. coli
	Reticulon-4, also known as Foocen, Neurite outgrowth inhibitor, Nogo protein, Neuroendocrine-specific protein, Neuroendocrine-specific protein C homolog, RTN-x, Reticulon-5 and RTN4, is a multi-pass membrane protein that...
TMPY-02712	Serpin B3 Protein, Human, Recombinant (His)	Human	Baculovirus Insect Cells
	SERPINB3, also known as SCCA-1, belongs to the serpin family. Serpins are a group of proteins with similar structures that were first identified as a set of proteins able to inhibit proteases. The acronym serpin was orig...
TMPJ-00685	BAI3 Protein, Human, Recombinant (His)	Human	HEK293 Cells
	Human Brain-Specific Angiogenesis Inhibitor 3 (BAI3) is a 177 kDa seven-span transmembrane (TM) protein, which is thought to be a member of the secretin receptor family. It is synthesized by neurons of the CNS and likely...
TMPK-01456	HLA-C03:04&B2M&KRAS G12D (GADGVGKSAL) Tetramer Protein*, Human, MHC (His & Avi)	Human	HEK293 Cells
	Kirsten rat sarcoma 2 viral oncogene homolog (KRAS) is the most commonly mutated oncogene in human cancer. The developments of many cancers depend on sustained expression and signaling of KRAS, which makes KRAS a high-pr...
------------------------ More ------------------------

14-3-3 beta/alpha Protein, Mouse, Recombinant (His)

TMPH-02472

Species: Mouse

Expression System: P. pastoris (Yeast)

14-3-3 beta/alpha Protein, Mouse, Recombinant (E. coli, His)

TMPH-02471

Species: Mouse

Expression System: E. coli

14-3-3 zeta/delta Protein, Mouse, Recombinant (His & SUMO)

TMPH-02473

Species: Mouse

Expression System: E. coli

PPP1R14A Protein, Human, Recombinant (His)

TMPJ-01261

Species: Human

Expression System: E. coli

Serpin A5 Protein, Human, Recombinant (His)

TMPJ-00490

Species: Human

Expression System: HEK293 Cells

DIT33 Protein, Dirofilaria immitis, Recombinant (His & Myc)

TMPH-00478

Species: Dirofilaria immitis

Expression System: E. coli

Barstar Protein, Bacillus amyloliquefaciens, Recombinant (His & Myc)

TMPH-00155

Species: Bacillus amyloliquefaciens

Expression System: E. coli

5T4/TPBG Protein, Cynomolgus, Recombinant (His & Myc)

TMPH-02437

Species: Cynomolgus

Expression System: HEK293 Cells

SPINK7 Protein, Human, Recombinant (His)

TMPJ-01032

Species: Human

Expression System: HEK293 Cells

Serpin E1 Protein, Mouse, Recombinant (His)

TMPJ-00625

Species: Mouse

Expression System: HEK293 Cells

5T4/TPBG Protein, Cynomolgus, Recombinant (E. coli, His & Myc)

TMPH-02436

Species: Cynomolgus

Expression System: E. coli

TFPI Protein, Human, Recombinant (His & Avi)

TMPK-00194

Species: Human

Expression System: HEK293 Cells

CCL3L1 Protein, Human, Recombinant (His)

TMPJ-00873

Species: Human

Expression System: HEK293 Cells

RP2 Protein, Human, Recombinant (GST)

TMPY-01203

Species: Human

Expression System: Baculovirus Insect Cells

TFPI Protein, Human, Recombinant (His & Avi), Biotinylated

TMPK-00195

Species: Human

Expression System: HEK293 Cells

TNNC1 Protein, Human, Recombinant (His)

TMPJ-00044

Species: Human

Expression System: E. coli

GHR Protein, Rhesus macaque, Recombinant (His)

TMPH-02440

Species: Rhesus

Expression System: E. coli

TNFRSF19 Protein, Human, Recombinant (His)

TMPK-01204

Species: Human

Expression System: HEK293 Cells

Serpin B1 Protein, Human, Recombinant (His)

TMPY-02128

Species: Human

Expression System: Baculovirus Insect Cells

LILRB3 Protein, Mouse, Recombinant (aa 25-642, His)

TMPH-02757

Species: Mouse

Expression System: HEK293 Cells

GHR Protein, Rabbit, Recombinant (His & Myc)

TMPH-03204

Species: Rabbit

Expression System: E. coli

TNFRSF19 Protein, Human, Recombinant (hFc)

TMPK-01203

Species: Human

Expression System: HEK293 Cells

GHR Protein, Pig, Recombinant (His)

TMPH-03112

Species: Sus scrofa (Pig)

Expression System: E. coli

SPINK2 Protein, Mouse, Recombinant (His & Myc)

TMPH-02898

Species: Mouse

Expression System: E. coli

DUSP14 Protein, Human, Recombinant (His & MBP)

TMPY-02595

Species: Human

Expression System: E. coli

FGF-5 Protein, Human, Recombinant (GST & His & Myc)

TMPH-01335

Species: Human

Expression System: E. coli

Thrombomodulin Protein, Mouse, Recombinant (His)

TMPJ-00857

Species: Mouse

Expression System: HEK293 Cells

SLPI Protein, Mouse, Recombinant (hFc)

TMPK-00924

Species: Mouse

Expression System: HEK293 Cells

Varicella-zoster virus (strain Dumas) glycoprotein L/gL Protein (His & Myc)

TMPH-03684

Species: HHV-3

Expression System: E. coli

Varicella-zoster virus (strain Oka vaccine) glycoprotein L/gL Protein (His & Myc)

TMPH-03685

Species: HHV-3

Expression System: E. coli

SLPI Protein, Human, Recombinant (hFc)

TMPK-00767

Species: Human

Expression System: HEK293 Cells

Sbi Protein, S. aureus, Recombinant (Avi & His & MBP), Biotinylated

TMPH-03559

Species: Staphylococcus aureus

Expression System: E. coli

Beta-casein Protein, Bovine, Recombinant (His & Myc)

TMPH-00227

Species: Bovine

Expression System: E. coli

JNK2 Protein, Human, Recombinant (His)

TMPY-04550

Species: Human

Expression System: Baculovirus Insect Cells

MMP-26 Protein, Human, Recombinant

TMPY-04100

Species: Human

Expression System: E. coli

PPIL2 Protein, Human, Recombinant (aa 280-457, His)

TMPY-03413

Species: Human

Expression System: E. coli

CDKN2C Protein, Human, Recombinant (His)

TMPJ-00963

Species: Human

Expression System: E. coli

Serpin A5 Protein, Mouse, Recombinant (His)

TMPH-02832

Species: Mouse

Expression System: Baculovirus Insect Cells

IL-18BPd Protein, Mouse, Recombinant (hFc)

TMPJ-00072

Species: Mouse

Expression System: HEK293 Cells

Kallikrein 2/KLK2 Protein, Human, Recombinant (His)

TMPJ-00891

Species: Human

Expression System: HEK293 Cells

Coagulation factor VII/F7 Protein, Human, Recombinant (His)

TMPY-02014

Species: Human

Expression System: HEK293 Cells

Serpin G1 Protein, Human, Recombinant (His)

TMPJ-00502

Species: Human

Expression System: HEK293 Cells

Vitronectin Protein, Human, Recombinant (Truncated, His)

TMPJ-00472

Species: Human

Expression System: HEK293 Cells

IGFBP-7 Protein, Mouse, Recombinant (His)

TMPJ-01166

Species: Mouse

Expression System: HEK293 Cells

Cystatin SN Protein, Human, Recombinant (His)

TMPY-02070

Species: Human

Expression System: HEK293 Cells

CXCL4 Protein, Human, Recombinant

TMPY-00741

Species: Human

Expression System: E. coli

RTN4 Protein, Human, Recombinant (GST)

TMPY-02001

Species: Human

Expression System: E. coli

Serpin B3 Protein, Human, Recombinant (His)

TMPY-02712

Species: Human

Expression System: Baculovirus Insect Cells

BAI3 Protein, Human, Recombinant (His)

TMPJ-00685

Species: Human

Expression System: HEK293 Cells

HLA-C*03:04&B2M&KRAS G12D (GADGVGKSAL) Tetramer Protein, Human, MHC (His & Avi)

TMPK-01456

Species: Human

Expression System: HEK293 Cells

--------- More ---------

Cat No.	Product Name
L7600	Chemokine Inhibitor Library		59 compounds
	A unique collection of 59 chemokines or chemokine receptors targeted compounds for high throughput and high content screening;

Libraries

Chemokine Inhibitor Library

L7600

Compounds: 59